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Twice subacute MPTP administrations induced time-dependent dopaminergic neurodegeneration and inflammation in midbrain and ileum, as well as gut microbiota disorders in PD mice

Briefly, mice exhibiting the FUSALS phenotype (characterized by FUS translocation from the nucleus to the cytoplasm) demonstrated longer lifespan, reduced disease severity and improved histological patterns when intracellular HSPA1A was overexpressed (Piavchenko et al., 2024

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